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Clickable Table of Content

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Regex Examples

Regex Search Box Effect
snora2 snora2\D snoRNA Names Show snoRNAs with the same name and if they have varying end letters
nr_\d+ External IDs Show all entries with a Refseq ID
hgnc:\d+ External IDs Show all entries with an HGNC ID
hgnc:\d.*ensg\d.*nr_\d+ External IDs Show all entries with an HGNC ID, an Ensembl ID & a Refseq ID
^(?!.*(hgnc|nr_)).*$ External IDs Show all entries without an HGNC or Refseq ID

Toggle Column Visibility with buttons

Columns are grouped by similar data types and color coded to match columns in their group

Individual columns can be toggled by clicking on Column Visibility

Reorder Columns & Select Rows


Drag and drop Columns (except Symbol) to re-order them. Hold Ctrl to prevent sorting of the column.

Click on rows to highlight them.

  • Hold Ctrl (Command on Mac) + Click = select non-contiguous rows
  • Hold Shift + Click = select contiguous rows

Highlighted rows can be downloaded (see next slide) or added to snoTHAW using a dedicated button in the widget (not shown here).

Download & Share Data From Query or Selection

Example: You obtain the following rows from a query and want to share them

  • Click the TSV or Excel download buttons. These files can be shared AND used to view their contents in snoDB once more by:
    • Copy/pasting a column into a related search engine on the site
    • Example: Click the first snoRNA Symbol in the file then click the last while holding Shift and copy/paste it into the snoRNA Symbol + Synonym search box in Columns Search

snoDB Use Case: SNORD118(U8) mutations are linked to Leukoencephalopathy


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As the article states:

"Despite the U8 snoRNA being ubiquitously expressed, germline mutations in SNORD118 cause an exclusively neurological, progressive microangiopathy"

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They conclude without establishing a causal link:

"The precise link between U8 and cerebral vascular homeostasis awaits elucidation and may conceivably involve a direct effect on translation or other yet to be defined functions of U8."

Had they had access to snoDB, they would have known that SNORD118 has predicted RNA interactions with cerebrally enriched genes EHD3 & ZNF536 (as we can see in the Next Slide >>>) which opens up potentially interesting avenues to investigate.