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Our group focuses on the characterization of biological pathways and mechanisms using genomics, bioinformatics and machine learning approaches. Our areas of interest revolve around the study of RNA and the regulation of protein subcellular localization.

 

 

 

 

 

 

 

 

 

 

We are currently particularly interested in:


-the biogenesis and function of small RNAs
-the genomic characterization of the targets of RNT1, prototypical type III yeast endonuclease
-the regulation of protein subcellular localization at the level of splicing
-the combinatorial action of splicing factors
-G-quadruplex identification and function

 

Our approach combines careful curation of the literature, analysis of high-throughput datasets (and in particular deep-sequencing datasets) and data integration to create predictors and models of molecular classes, biological pathways and systems.  Please watch the tools section as our databases and predictors become available.

We collaborate closely with wetlab research groups to generate our datasets and test our analyses and predictions in an iterative manner. Several members of our group are members of members of others such groups including Sherif Abou-Elela's and Jean-Pierre Perreault's groups.

 

Latest news

Another semester
This new semester brings few changes. Audrey, Daniel and Darren are back in classes while Félix is back with us for a second internship. We are welcoming Michaël Desgagné in the group for an intership as well.

Aug. 30, 2016

New interns for the 2016 summer semester
Pr. Scott's lab is proud to welcome Daniel Tucunduva and Darren Mathurin St-Pierre as interns for the 2016 summer semester. We would also like to extend the welcome to our new MSc. Candidate Gabrielle Deschamps-Francoeur.

June 15, 2016

New interns
We greet Félix and Gabriel in the research group for the winter 2016 semester.

Jan. 4, 2016

Da vinci Medal
Congratulations to Gabrielle Deschamps-Francoeur, intern in our group, for winning the Leonard Da Vinci Medal for excellence in Engineering at the UofS!

Dec. 15, 2015

Start of the school year 2015
We are glad to welcome Darren in the group and wish a good return to Audrey and Mikael.

Aug. 31, 2015

Publication of G4RNA
Congratulations to Jean-Michel, Mikael and Michelle for their paper published in Database.

July 24, 2015

New faces
A new semester has begun, we want to thank Mikael and Mikaël for their work and we welcome Philippe, Vincent and Lori.

May 5, 2015

Publication of a review in WIREs RNA
Fabien, Mikaël and Michelle just published a review on snoRNA: The emerging landscape of small nucleolar RNAs in cell biology.

April 16, 2015

Welcome to Mikael and Mikaël
We are glad to welcome Mikael Luce for his second internship and Mikaël Poirier for his first internship this winter.

Jan. 5, 2015